Can you replace the headunit in a 2004 acura tsx?

im looking into buying used 2004 acura tsx, now i know that im going to be buying my brothers subs off him and i want to put in a headunit. i want to put in one that had a touchscreen or flip up screen. would i be able to install that at somewhere like bestbuyCan you replace the headunit in a 2004 acura tsx?
Bestbuy does offer the service.

sea doo